Investment professional – Hledam http://hledam.biz/ Thu, 07 Oct 2021 13:06:27 +0000 en-US hourly 1 https://wordpress.org/?v=5.8 https://hledam.biz/wp-content/uploads/2021/06/icon-2021-07-01T003219.761-150x150.png Investment professional – Hledam http://hledam.biz/ 32 32 UM’s student-run investment fund targets start-up climate technology companies https://hledam.biz/ums-student-run-investment-fund-targets-start-up-climate-technology-companies/ https://hledam.biz/ums-student-run-investment-fund-targets-start-up-climate-technology-companies/#respond Thu, 07 Oct 2021 13:00:01 +0000 https://hledam.biz/ums-student-run-investment-fund-targets-start-up-climate-technology-companies/ University of Michigan students and faculty have launched a student-run investment fund targeting start-up climate technology companies that aim to make a real difference on climate change. The fund is the centerpiece of the Michigan Climate Venture, a one-of-a-kind multidisciplinary program at the intersection of climate technology and venture capital at UM. The program is […]]]>

University of Michigan students and faculty have launched a student-run investment fund targeting start-up climate technology companies that aim to make a real difference on climate change.

The fund is the centerpiece of the Michigan Climate Venture, a one-of-a-kind multidisciplinary program at the intersection of climate technology and venture capital at UM. The program is designed to provide a hands-on learning experience that will prepare students for impactful careers in the fight against climate change.

It was developed by professors and MBA students from the Ross School of Business in partnership with UM’s School for the Environment and Sustainability and Erb Institute.

“MCV seeks to be a distinctive educational experience at a leading public research university: problem-oriented and action-oriented, rigorous and data-driven, multidisciplinary, enhanced by technology, and co-created and managed by students “, said Gautam Kaul, the fund’s faculty director and professor of finance and professor Robert G. Rodkey Collegiate of Ross Business Administration.

“MCV is based on the success of the Social Venture and International Investment funds, which I also oversee at Michigan Ross, and is in partnership with the Erb Institute and SEAS, and focuses on the most pressing and most pressing global societal issue. challenge we face: climate change. “

Based at SEAS, the MCV fund is the first student-run fund outside of Michigan Ross at UM, Kaul said. It is open to full-time graduate students from schools across campus to take advantage of the expertise that can be found at the university. The fund also adopts the principles of diversity, equity and inclusion in its recruitment, experience and operations.

This year, approximately 20 students have been accepted into the fund, including full-time MBA students from Ross as well as those from SEAS and the College of Engineering. Throughout the academic year, members will collaborate to research, select, control and ultimately invest and support agreements aligned with the fund’s mission.

The founding management team of the fund consists of seven full-time Ross MBA students who are also double degree students at the Erb Institute: Sam Buck, Laura Dyer, Janet Genser, Chelsea Parker, John Pontillo, Olivia Rath and Colleen Sain. Two Michigan Ross alumni, Joe Garcia and Leah Gustafson, also worked with Kaul to conceptualize and recruit members to start the fund, and dual degree student Celia Bravard helped create the impact assessment framework. of the fund during the summer.

“Michigan Ross, and UM at large, are distinguished by their focus on creating positive impact, strong action-based learning opportunities and a vibrant learning community,” said Rath, who co-leads the education component of the fund.

“MCV embodies each of these elements: it combines students with a wide range of personal and professional experiences, perspectives and lived experiences to embark on shared learning and practical experience of assessment and investment in technologies and solutions to help mitigate global climate change. “

Genser said the team spent the last year defining and refining the fund’s investment thesis, the group’s culture, the fund’s operations and the role they wanted the fund to play at university. and in the broader climate technology venture capital landscape.

“We hope to be the ‘hub’ for climate on campus, which means we are connected to most student groups, climate research labs and climate-focused events on campus,” a- she declared. “We have a vision that perhaps one day MCV will also become an incubator for climate technology startups, and we hope to be the first of many university climate funds.”

Pontillo said he thinks MCV is important for many reasons, starting with the possibility for students to have hope for the future of the planet.

“We all face an uncertain future in which lives around the world will be affected by the increasingly serious consequences of climate change. We must devise a method to face and combat this challenge in a sustainable and hopeful way, ”he said. “MCV does just that, while allowing students to teach and learn together, so they can use what they have learned in MCV and incorporate it into their careers to expand their anti-change efforts.” climate. “

Sain, who has a background in startups and software engineering, said she joined MCV because she felt it was a perfect way to make an impact now, while also gaining the skills she will need. long-term.

“Having worked in startups at different stages, both before and during graduate school, I have witnessed firsthand the power to inject capital into the bold visions of a passionate founder,” Sain said. “Considering our world’s most pressing problem, the creation of MCV aimed to harness UM’s excellence in entrepreneurship studies and the history of student-run impact funds to meet the needs of entrepreneurs. in sustainable development that innovate in the area of ​​decarbonization. “

After being a member of the Social Venture Fund for two years, Buck also said that leading MCV fits well with his career goals.

“I came to UM to develop a skill set that would allow me to step out of the sidelines and become an active contributor to finding creative solutions,” he said. “MCV provides students with the tools and experience to dive head first into climate space and make a real impact today. Students will be ready to go as soon as they graduate.

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Changes could be made to the federal student loan exemption program https://hledam.biz/changes-could-be-made-to-the-federal-student-loan-exemption-program/ https://hledam.biz/changes-could-be-made-to-the-federal-student-loan-exemption-program/#respond Wed, 06 Oct 2021 21:50:08 +0000 https://hledam.biz/changes-could-be-made-to-the-federal-student-loan-exemption-program/ News 12 Staff Oct 06, 2021, 9:47 PM Updated: Oct 06, 2021, 9:47 PM Federal student loan borrowers are cautiously optimistic about the changes on the horizon for the federal student loan waiver program. “I don’t feel like there is enough advice on how to be forgiven,” says Dr Andrea Thomas. “So there is a […]]]>

Federal student loan borrowers are cautiously optimistic about the changes on the horizon for the federal student loan waiver program.

“I don’t feel like there is enough advice on how to be forgiven,” says Dr Andrea Thomas. “So there is a part of me that lacks faith in the actual process of forgiveness.”

The program was first introduced in 2007. The head of the education ministry said changes to the program would include a review of refused applications and the entire process.

A time-limited waiver to allow past payments to count toward their loan will be available to borrowers.

For members of military service, active service will also be taken into account in the program.

Investment professional Mitchell Goldberg says that with 1 in 8 Americans with student debt, he thinks the program overhaul is good news.

“It will help almost immediately, 550,000 people – as long as they are aware that this program exists and that is the key,” Goldberg said.

The goal of the program is to write off a portion of the federal student loan debt for eligible public sector workers after they have made 10 years of monthly payments.

Senator Chuck Schumer (D-NY) wants the Biden administration to write off up to $ 50,000 in student debt for each borrower.

Goldberg cautions borrowers because of the political wrangling over the infrastructure bill and social spending programs, not to count on this $ 50,000 pardon. The focus may not be on canceling student loans.

“People should start preparing to repay their loans in January. Don’t wait, ”he said.


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CLA (CliftonLarsonAllen) opens Nashville office for https://hledam.biz/cla-cliftonlarsonallen-opens-nashville-office-for/ https://hledam.biz/cla-cliftonlarsonallen-opens-nashville-office-for/#respond Wed, 06 Oct 2021 13:38:17 +0000 https://hledam.biz/cla-cliftonlarsonallen-opens-nashville-office-for/ Nashville, Oct 06, 2021 (GLOBE NEWSWIRE) – Today, CLA (CliftonLarsonAllen LLP), one of the leading professional services firms in the United States, announced the official opening of its Nashville office, marking the first steps in its efforts to bring its outsourcing, asset advisory, audit, tax and advisory services to the city. The office is located […]]]>

Nashville, Oct 06, 2021 (GLOBE NEWSWIRE) – Today, CLA (CliftonLarsonAllen LLP), one of the leading professional services firms in the United States, announced the official opening of its Nashville office, marking the first steps in its efforts to bring its outsourcing, asset advisory, audit, tax and advisory services to the city. The office is located at 150 4th Avenue North, Suite 1820.

Earlier this year, CLA announced its expansion to Nashville to capitalize on market growth in Nashville and the surrounding area in areas such as healthcare, private equity, manufacturing and distribution, real estate. and technology.

“We are thrilled to celebrate our work in the Nashville Marketplace with the official opening of the office,” said Jen Leary, CEO of CLA. “The Nashville market is poised for innovation and growth, and we believe there will be many opportunities to bring our seamless customer experience approach to the community.”

“TVA and NES congratulate CLA on their decision to locate their business in Nashville,” said John Bradley, senior vice president of economic development for TVA. “Helping support businesses, like CLA, as they create employment and investment opportunities in the Valley is fundamental to TVA’s service mission and we are proud to partner with the Nashville Area Chamber to move forward this mission and celebrate this announcement together. ”

CLA continues to serve clients of all sizes in various sectors of the Nashville market, with increasing traction in healthcare, private equity and real estate. The CLA team in Nashville is led by Mike Slavik, head of enterprise-wide expansion and general manager of the office, and Mark Wyzgowski, director, who leads the local private equity business.

“CLA is different from a lot of other big companies in Nashville,” Slavik said. “I was asked what the minimum size of our clients is, and I don’t even have an answer to that. We have created a model that allows us to serve small entrepreneurial organizations as well as the largest public enterprises in the country. We look forward to working with local leaders to bring innovative approaches to our customers and our community. ”

CLA is committed to engaging in the community to support the continued growth and business innovation of Nashville. CLA also encourages members of the CLA family to get involved with local nonprofit organizations. CLA began working earlier this year with the Nashville Entrepreneur Center, as a program partner for Twende’s pre-flight and in-flight organizations. The relationship with the Nashville Entrepreneur Center has led to participation in additional programs, such as the Nashville Health Care Council and EO Nashville.

For more information, visit CLAconnect.com.

About CLA

CLA exists to create opportunities for our clients, employees and communities through industry-focused wealth advisory, outsourcing, auditing, tax and advisory services. With 7,400 people, over 120 locations in the United States, and a worldwide affiliation, we promise to know and help you. For more information, visit CLAconnect.com. Investment advisory services are offered by CliftonLarsonAllen Wealth Advisors, LLC, an investment adviser registered with the SEC.

        


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A private equity firm sells Zenith https://hledam.biz/a-private-equity-firm-sells-zenith/ https://hledam.biz/a-private-equity-firm-sells-zenith/#respond Wed, 06 Oct 2021 01:54:00 +0000 https://hledam.biz/a-private-equity-firm-sells-zenith/ Zenith Investment Partners has been sold to a London-based data feed and technology provider for an undisclosed amount. Private equity firm Five V Capital sold Zenith to FE fundinfo less than two years after its acquisition. Zenith CEO David Wright said: “Management agrees that there is a great alignment of values ​​and goals between the […]]]>

Zenith Investment Partners has been sold to a London-based data feed and technology provider for an undisclosed amount.

Private equity firm Five V Capital sold Zenith to FE fundinfo less than two years after its acquisition.

Zenith CEO David Wright said: “Management agrees that there is a great alignment of values ​​and goals between the two organizations, and that together we can create a truly premium service. compelling for advisors, fund managers, super funds and client institutions. “

The research house was founded 20 years ago. He has evaluated over 1,000 investment and retirement funds and 150 investment portfolio solutions.

Five V Capital investment professional Angus Whitehead has said from the start of the partnership: “Zenith has achieved transformational growth and we are proud to support David Wright and his team on this journey.”

“Now, with the global reach and growth program of FE fundinfo, we believe the company is well positioned to continue to build on this platform and improve its service offerings for clients in the years to come. come, ”he said.

FE fundinfo chief executive Hamish Purdey said the deal brings together two providers of fund and research data in Europe and the APAC region with a complementary set of services focused on asset managers and advisers.

This is the second acquisition of FE fundinfo in Australia. She acquired Chant West in 2020.


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Poets & Quants – Chicago Booth Neubauer Civic Scholars https://hledam.biz/poets-quants-chicago-booth-neubauer-civic-scholars/ https://hledam.biz/poets-quants-chicago-booth-neubauer-civic-scholars/#respond Tue, 05 Oct 2021 05:00:20 +0000 https://hledam.biz/poets-quants-chicago-booth-neubauer-civic-scholars/ Students work in nonprofit organizations, government, healthcare, and developing economies. They are passionate about doing well and doing good – applying the rigors of an MBA from Chicago Booth to generate greater social impact. They are mid-career professionals at Booth’s Civic Scholars Program, dedicated to careers in the non-profit or government sector and receiving up […]]]>

Students work in nonprofit organizations, government, healthcare, and developing economies. They are passionate about doing well and doing good – applying the rigors of an MBA from Chicago Booth to generate greater social impact. They are mid-career professionals at Booth’s Civic Scholars Program, dedicated to careers in the non-profit or government sector and receiving up to 100% tuition support. If you are an emerging leader and want to join a highly motivated group interested in innovation, advancing research, and developing people and practices that accelerate social change, consider applying to the Civic Scholars Program.

FOLLOWING

Launched in 2016 with the support of the Neubauer Family Foundation, our Neubauer Civic Scholars are selected each year and have the option of enrolling in the full-time MBA, evening MBA or weekend MBA programs of Booth. You will join a tight-knit group of professional colleagues from the public and social sectors throughout your MBA journey. As a Civic Scholar, you will experience the breadth of the Booth MBA program – strategy, operations, leadership, finance, economics, accounting, and other disciplines – that positions you to lead social sector organizations. Beyond the Chicago campus, you’ll also have access to our global community of over 54,000 Chicago Booth alumni.

Neubauer Civic Scholars benefit from the program’s close collaboration with Booth’s Rustandy Center for Innovation in the Social Sector, the school’s destination for people committed to helping solve complex social and environmental problems. The courses examine the role of business and the social sector in society and provide hands-on learning. The programming explores sustainability and climate change, social entrepreneurship and impact investing, and how philanthropy advances justice and equity.

Today, Civic Scholars program alumni are reinventing systems to provide equitable access to affordable, high-quality health care, helping rural households move out of poverty, tackling climate change, and investing in organizations. at the service of black and Latinx youth.

In the discussion below, find out why some of the diverse voices in our 2021 incoming class chose Booth and the Civic Scholars Program. Learn more and apply here.

Why Booth?

Ben Harris, Strategic Advisor for Health and Social Systems, Colorado Department of Health Care Policy and Funding, Denver

After more than a decade in public health care, I needed to refine my existing skills and add new skills to maximize my impact. I also wanted to reflect on my experience and make a plan for my future goals and impact with other experienced leaders from the public and social sectors. Booth’s prowess and reputation for developing highly skilled leaders who aren’t afraid to tackle complex issues immediately drew me to help me achieve my first goal. The Civic Scholars Program was the community where I was able to do extensive work of leadership thinking and development to achieve my second goal. Together, with the possibility of being back in Chicago, they fit together perfectly.

What is the value of the Civic Scholars program?

Jasmine Ferguson, Senior Operations and Compliance Associate, Rocketship Public Schools, Chicago

The Civic Scholars Program will allow me to create a network of peers who challenge and encourage each other not only to develop solutions, but to implement them. I will use my time at Booth to deepen my understanding of how to solve larger structural problems through a qualitative and quantitative approach, financial sustainability and organizational leadership. By harnessing my education and work experiences, I will merge business and social impact to create partnerships that can advance the efforts of community organizations and increase economic opportunities.

What is the value of an MBA for the nonprofit and public sectors?

Louisa Shepherd, Director of Collective Impact, Epicenter Memphis

Some people might think that nonprofits are less serious or less competitive than their for-profit counterparts. But I contend that, because nonprofits are often dedicated to solving the most pressing social problems on our planet, it is imperative that our work be led by exceptionally well-trained and well-prepared people. An MBA provides the tools and frameworks these leaders need to be successful. The societal challenges we face over the next few decades will be significant and the stakes will be high – which is why an MBA is such a critical part of my career development in the nonprofit sector.

How will you apply the skills you learn to Booth?

Aviva Kapust, Executive Director, The Village of Arts and Humanities, Philadelphia

At Booth, I want to build muscle to create long-term impact. As the Executive Director of an arts-based community development organization in one of Philadelphia’s most disinvested communities, I aim to develop my ability to strategically attract, manage and leverage smarter combinations of income, investment capital and human capital. Stand-alone courses such as Impact Investing, Social Sector Strategy and Structure, and Social Entrepreneurship and Innovation offer the knowledge, frameworks and tools that I am looking for. I am interested in learning how to tailor market-based interventions for social impact that promotes long-term systemic change.


Wai-Sinn Chan is Director, Social Sector Engagement Programs and Civic Scholars at Rustandy Center for Innovation in the Social Sector at the Chicago booth. She leads the social sector engagement strategy and programming for students and alumni, and manages the Civic Scholars Program. Her too collaborates with Booth Career Services and other partners to develop new initiatives and resources for alumni interested in leveraging their business toolkit to work in social impact or engage in a nonprofit board.


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Marsh McLennan publishes Oliver Wyman Forum’s Climate Action Navigator https://hledam.biz/marsh-mclennan-publishes-oliver-wyman-forums-climate-action-navigator/ https://hledam.biz/marsh-mclennan-publishes-oliver-wyman-forums-climate-action-navigator/#respond Mon, 04 Oct 2021 15:03:00 +0000 https://hledam.biz/marsh-mclennan-publishes-oliver-wyman-forums-climate-action-navigator/ As part of a company-wide effort to help customers halve their emissions by 2030 NEW YORK, October 04, 2021– (COMMERCIAL THREAD) – Today, Marsh McLennan (NYSE: MMC), the global leader in professional services in risk, strategy and human resources, unveiled the Climate Action Navigator from the Oliver Wyman Forum. The Navigator helps senior leaders explore […]]]>

As part of a company-wide effort to help customers halve their emissions by 2030

NEW YORK, October 04, 2021– (COMMERCIAL THREAD) – Today, Marsh McLennan (NYSE: MMC), the global leader in professional services in risk, strategy and human resources, unveiled the Climate Action Navigator from the Oliver Wyman Forum. The Navigator helps senior leaders explore the steps they need to take to enable us to halve emissions by 2030, keeping a 1.5 degree temperature rise within reach.

The Climate Action Navigator helps public and private sector leaders chart a course through climate science. It identifies the emission levels of 22 industrial sectors in 12 regions of the world and quantifies the effects of different carbon emission reduction strategies.

The Climate Action Library brings together, for the first time, an impact assessment of several different mitigation measures, including changes in energy and fuel use, construction and heating of buildings, in industrial processes and transportation, in land use and food efficiency, and in negative emission technologies. The effect of each mitigation strategy can be analyzed for each sector and region, giving business and government leaders critical information to meet their climate targets by 2030.

“Marsh McLennan aims to be an important catalyst for low carbon and climate change resilient investments in the business sector,” said Nick Studer, CEO of Oliver Wyman and Vice President of Marsh McLennan. “We’re developing cutting-edge data and analytics like the Climate Action Navigator to bring the public and private sectors together to solve real problems. The Navigator will help our clients understand the speed of change needed, assess options and develop resilient strategies for the future. “

The Climate Action Navigator is part of the efforts of Marsh McLennan’s four companies, under the leadership of Mr. Studer, to help clients integrate climate planning into their risk, strategy and people decision making.

Risk

Marsh McLennan through his activities Marsh and Guy Carpenter, advises companies and governments on climate risk and the low carbon transition. He helps clients understand and quantify climate risk and works with companies and public sector clients to manage capital, volatility and growth while navigating global climate-related regulatory stress tests and requirements. disclosure. It supports clean energy developers through a globally integrated renewable energy business and helps traditional energy producers make the transition to clean energy production.

The Company also provides catastrophe modeling, advisory and reinsurance services to the world’s largest insurance and catastrophe risk programs, including the United States National Flood Insurance Program and Flood Re in the United States. United Kingdom, to help reduce the economic impact of climate-related losses and enable investment in more sustainable communities. It is committed to creating new innovative products, dynamic risk modeling tools that integrate climate change scenarios and establishing new capital models to accelerate the transition to a low carbon future.

Strategy

Oliver Wyman works with clients to develop transition strategies across all sectors of the economy, particularly high impact transitions in financial services, energy and power, transportation, manufacturing and industry heavy. Mercer, a pioneer in sustainable investing, helps asset owners identify and manage climate risks in investment portfolios through research and advisory frameworks, as well as tools and solutions that can support Implementation. Mercer believes that embedding sustainability into investment beliefs, policies, processes and portfolios can help improve client outcomes.

People

Mercer also helps clients navigate culture and workforce transformation. This includes advising organizations on how to more fully integrate sustainability and the common goal into workforce cultures in the face of the low carbon transition. The Mercer People Sustainability Index advises institutions on where they stand relative to others in the marketplace and helps clients establish a strategic plan and culture to help businesses achieve their goals by achieving a healthy, resilient and resilient future. fair.

Climate commitments

Marsh McLennan is committed to sustainability. In 2020, the Company adhered to the recommendations of the Task Force on Climate-related Financial Disclosures (TCFD) and published its first report aligned with the TCFD in 2021. It has also been CarbonNeutral® certified since September 1, 2021 in accordance with the CarbonNeutral Protocol, and pledged to reduce its carbon emissions by 15% from 2019 levels by 2025.

His companies have worked with organizations such as the CDP, the World Economic Forum, the United Nations Environment Program Finance Initiative and The Nature Conservancy, to establish new agendas and build consensus on the issue of climate change. . Most recently, Oliver Wyman and the Climate Group presented a plan for a commercially smart climate transition, distilling insights from some of the world’s most experienced business climate action leaders on how they turn climate commitments into tangible results. .

More information on how Marsh McLennan brings together its business and capabilities to help clients anticipate climate risks and opportunities is available here.

About Marsh McLennan

Marsh McLennan (NYSE: MMC) is the global leader in professional services in the areas of risk, strategy and human resources. The Company’s 78,000 employees advise clients in 130 countries. With annual sales of over $ 18 billion, Marsh McLennan helps clients navigate an increasingly dynamic and complex environment across four market-leading companies. Marsh provides data-driven risk advisory and insurance solutions to business and consumer clients. Guy Charpentier develops advanced risk, reinsurance and capital strategies that help clients grow profitably and seize emerging opportunities. Mercier provides technology-driven advice and solutions that help organizations redefine the world of work, reshape retirement and investment outcomes, and unleash the health and well-being of a workforce evolving. Olivier Wyman serves as a critical strategic, economic and brand advisor to the private sector and government clients. For more information visit mmc.com, Follow us on LinkedIn and Twitter or subscribe to EDGE.

Oliver Wyman Forum

The Oliver Wyman Forum is committed to bringing together leaders from business, public policy, social enterprises and academia to help solve the world’s toughest problems. The Oliver Wyman Forum strives to discover and develop innovative solutions by conducting research, bringing together leading thinkers, analyzing options and inspiring action on three fronts: Cropping industry, Business in society, and Global economic and political change. With our growing and diverse community of experts, we believe we can make a difference. For more information visit www.oliverwymanforum.com.

See the source version on businesswire.com: https://www.businesswire.com/news/home/20211004005665/en/

Contacts

Amelia Woltering
Marsh McLennan
+1 347 703-5358
amelia.woltering@mmc.com



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Patient engagement: investing in the future of your product https://hledam.biz/patient-engagement-investing-in-the-future-of-your-product/ https://hledam.biz/patient-engagement-investing-in-the-future-of-your-product/#respond Sun, 03 Oct 2021 13:00:21 +0000 https://hledam.biz/patient-engagement-investing-in-the-future-of-your-product/ Participants in clinical trials are difficult, expensive, and time consuming to recruit, making it one of the most valuable assets of a study. Yet across the industry, dropout rates are noticeably high. As drug development becomes more expensive, focused and complex, each topic listed is more important than ever. Investing in patient engagement strategies that […]]]>

Participants in clinical trials are difficult, expensive, and time consuming to recruit, making it one of the most valuable assets of a study. Yet across the industry, dropout rates are noticeably high.

As drug development becomes more expensive, focused and complex, each topic listed is more important than ever. Investing in patient engagement strategies that make enrollment easier and keep people on board, on track, and on medication might be the answer developers have been looking for.

The recruitment problem

Recruitment for clinical trials is a huge challenge for drug development, contributing to the delay and even failure of the study.

A 2018 review factors associated with failure of clinical trials, such as David Fogel, described it as a “long standing problem”. A study of 114 trials in the UK, he said, found that only 31% met their recruitment targets, and a third of publicly funded trials needed an extension because they did not meet the initial recruitment goals.

Some reports estimate that up to 50% of tests start late because they do not recruit enough participants in the allotted time. This is an important figure when delays can cause between $ 600,000 and $ 8 million a day of losses.

Lack of awareness, fear or misconceptions about what a clinical trial entails, as well as strict eligibility criteria are all factors that contribute to low recruitment rates and together they serve to create a funnel. increasingly close to willing and suitable candidates.

For all these reasons and many more, it can cost on average of $ 6,533 to recruit only one patient in a clinical study. This means that recruitment represents a substantial part of the estimate. $ 314 million to $ 2.8 billion developing and bringing a new drug to market can be expensive.

The problem of retention

As most sponsors and CROs painfully know, recruiting is only half the battle. Even when studies recruited enough people to begin testing, about 30% of participants end up giving up. And the longer the follow-up, the higher the dropout rate.

The reasons are varied, but they include the financial and logistical implications of participating in site visits and a lack of understanding of the trial protocol. Whatever the reason, the impact cannot be overstated.

When a trial experiences too many dropouts, whether based on planned or actual registrations, the trial can become undernourished. There may not be enough data to effectively demonstrate a statistically significant clinical benefit or the safety of the product.

Fogel in his 2018 review, said: “Undernourished clinical trials are problematic. The sponsor can adapt to low recruitment by increasing the number of sites (possibly in other countries, with corresponding expensive protocol changes and delays in further research), increasing the funds allocated to the study in order to achieve the minimum recruitment.

This burden, he continued, sometimes necessitates the elimination of certain scheduled tests in order to reallocate available funds and, in turn, some parameters may have an insufficient sample size to detect an important result.

For decades, sponsors and CROs have attempted to fill this gap by recruiting replacement participants. But not only is this strategy insanely expensive, the era of personalized medicine is quickly making it unachievable.

With the development of more complex and more targeted drugs, the eligibility criteria for clinical trials are more restricted. Trials of products aimed at smaller patient populations, such as those with a particular genetic mutation, for example, have a smaller pool of potential candidates to tap into, making “back-to-the-drawing board recruitment” a priority. diminishing returns approach.

Retaining the initial admission of registered participants, then, has never been more important financially or scientifically.

Engage your participants

Focusing on patient engagement can help overcome the long-standing challenge of retaining clinical trial participants by giving people everything they need to become – and stay – invested in the process.

This journey begins at the very beginning of a trial. The patient-centered study design can minimize protocol burden by ensuring that it does not include, for example, an unrealistic number of site visits or invasive procedures.

Prior to registration, teams should work with participants to ensure they understand exactly what is expected of them and what they can expect from the trial. Consent forms, for example, should be written to take into account different levels of health literacy to give people the best chance to start the process with their eyes wide open.

To be successful, however, engagement strategies must span the duration of the study, constantly checking in with participants to make sure they are on the right track and offering support where and when needed.

This may seem difficult, especially as the sector moves more towards the decentralized model and eliminates many face-to-face interactions.

However, by focusing on treatment adherence, teams can constantly monitor participants for signs of waning engagement that may lead to dropouts.

Membership: a barometer of commitment

Adherence to medication is widely accepted as a marker of engagement with the management of the disease under long-term conditions. The approach has just as much to offer in the field of clinical trials.

Monitoring treatment adherence can provide a wealth of information about participants’ investment in the study. Non-compliance can be a harbinger of abandonment. It offers clues to poor product efficacy, intolerable side effects, or administration issues, all of which can lead to poor retention.

However, measuring drug-taking behavior can be difficult. Traditional validated adherence measures are rare and those that do exist are non-standard and imperfect.

Moreover, even when study teams see non-adherence, then they are faced with the dilemma of what to do about it. There are many reasons for poor adherence and interventions must be personalized for both the drug and the patient.

Digital membership monitoring can help by incorporating smart packaging and powerful analytics to spot when people might need additional assistance to stay on track.

Digital approach

Digital membership monitoring can improve recruiting, by reducing the load that can discourage people from signing up in the first place, and improve retention, by helping teams keep people engaged in the study.

Smart drug packaging automatically records dose delivery. Connected smart blisters, for example, can collect not only the time and date of pill withdrawal, but also the open pill cavity, number of tablets withdrawn, kit number and expiration date.

This means that dosage histories are compiled without participants needing to keep a diary or register while taking their medications, for example.

The captured information is then fed to a cloud-based platform, which provides sophisticated analysis of medication-taking behaviors and creates powerful visualization and targeted feedback for study teams and participants. It can even be integrated with third-party apps, such as patient apps designed to build engagement and encourage adherence throughout the study.

Study teams can use this information to identify those whose engagement may be waning and deploy personalized interventions to mitigate issues.

This approach works – the closed feedback loop of active surveillance and targeted actions can increase engagement, resulting in a reduction of up to 50% in dropouts.

Ultimately, digital membership tracking is 97% accuracy, compared to 60% for pill counting, 50% for healthcare professional assessment and only 27% for self-assessment, and that provides full understanding patient adherence behaviors and risk indicators that matter most to subject engagement and study success.

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CoinShares Chief Strategist Analyzes Way Forward For Bitcoin, Says Lots Of Money On The Sidelines https://hledam.biz/coinshares-chief-strategist-analyzes-way-forward-for-bitcoin-says-lots-of-money-on-the-sidelines/ https://hledam.biz/coinshares-chief-strategist-analyzes-way-forward-for-bitcoin-says-lots-of-money-on-the-sidelines/#respond Sat, 02 Oct 2021 18:46:58 +0000 https://hledam.biz/coinshares-chief-strategist-analyzes-way-forward-for-bitcoin-says-lots-of-money-on-the-sidelines/ CoinShares Chief Strategy Officer Meltem Demirors believes Bitcoin is poised to rise over the next few months as capital from sidelined investors is pushed into the crypto asset. In a recent interview on CNBC Television, the CEO of the digital asset management company highlights the potential catalysts that can push Bitcoin’s value to higher heights […]]]>

CoinShares Chief Strategy Officer Meltem Demirors believes Bitcoin is poised to rise over the next few months as capital from sidelined investors is pushed into the crypto asset.

In a recent interview on CNBC Television, the CEO of the digital asset management company highlights the potential catalysts that can push Bitcoin’s value to higher heights in the months to come.

“Right now we are hearing rumors around a potential Bitcoin ETF approval. This would be contract-based, cash-settled ETFs, but there is still a lot of ‘buy rumor, sell news behavior’ in crypto, this is a big catalyst that we are looking at in this section. fourth trimester.

There are also not a lot of open long positions in the Bitcoin position anymore, so we are seeing a lot more companies taking bullish long calls. In fact, there are a number of six-figure long-term call options that are in action at the end of the fourth quarter and the start of the first quarter. “

She also mentions that the wide variety of platforms being developed to buy Bitcoin will likely accelerate asset growth towards the end of this year.

“And I think the most important thing, honestly, is that there is a lot of money on the sidelines, and a lot of investors are now seriously considering an allocation to Bitcoin in their portfolios. There are now so many different ways to do this, whether through a publicly traded investment vehicle, or through assets themselves on platforms like Coinbase, or Robinhood, or Square. . The [are] just an absolute plethora of options that pave the way for retail and professional investors to gain exposure to the asset class.

I

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IPC Systems Announces Global Agreement to Reduce Debt and Provide Significant Equity to Support Long-Term Business Plan https://hledam.biz/ipc-systems-announces-global-agreement-to-reduce-debt-and-provide-significant-equity-to-support-long-term-business-plan/ https://hledam.biz/ipc-systems-announces-global-agreement-to-reduce-debt-and-provide-significant-equity-to-support-long-term-business-plan/#respond Fri, 01 Oct 2021 19:17:00 +0000 https://hledam.biz/ipc-systems-announces-global-agreement-to-reduce-debt-and-provide-significant-equity-to-support-long-term-business-plan/ NEW YORK, October 1, 2021 / PRNewswire / – IPC Systems, Inc. (“IPC” or the “Company”), a leading global provider of secure and compliant communication and networking solutions for global financial markets, announced today hui having entered into a transaction support agreement (the “Agreement”) with its key stakeholders, which will reduce the Company’s debt by […]]]>

NEW YORK, October 1, 2021 / PRNewswire / – IPC Systems, Inc. (“IPC” or the “Company”), a leading global provider of secure and compliant communication and networking solutions for global financial markets, announced today hui having entered into a transaction support agreement (the “Agreement”) with its key stakeholders, which will reduce the Company’s debt by more than $ 400 million, extend the maturity of its debt by 5 years and bring in new capital of $ 125 million provide the necessary resources for investment in long-term growth strategies.

Bob santella, CEO of IPC, said, “The balance sheet improvements we are announcing today will allow us to continue to build a strong future for IPC and to strengthen our partnership with employees, customers, suppliers and other relationships. strategic. I am particularly excited to accelerate our efforts. providing our customers with new and innovative solutions for their critical challenges – through both organic and inorganic actions in the months and years to come. We are also encouraged and grateful to have the support of our shareholders and lenders, which reflects their high level of confidence in us. “

Parties to the Agreement include: funds managed by Strategic Value Partners, LLC and its affiliates (“SVPGlobal“), a lender who, as a result of this transaction, will become a major sponsor and shareholder of shares; the affiliates of Centerbridge Partners, LP (“Centerbridge”), the Company’s current private equity sponsor, who will continue to be a significant shareholder; and some of its current major lenders, including HPS Investment Partners, LLC. HPS will continue to be IPC’s primary lender and lead a single group of lenders in a new streamlined debt structure.

Victor Khosla, Founder and Chief Investment Officer of SVPGlobal, said: “We firmly believe that with today’s agreement, IPC will maintain its position as a global leader in communication and networking solutions for the long term. We are delighted to renew our partnership with IPC and, in our more active role, we look forward to supporting management as they continue to provide the top-notch services for which they are known. “

Jared hendricks, Senior Managing Director of Centerbridge, said, “IPC has an excellent track record of delivering innovative solutions to the world’s leading financial institutions, and Bob has done a tremendous job at the helm of the company since joining in 2018. We look forward to continuing to support IPC, Bob and his leadership team in their next phase of innovation and growth. “

Mr. Santella continued, “At IPC, we pride ourselves on helping our clients anticipate changes and solve problems, and this is also true of the way we run our multiple award-winning business. For nearly fifty years, we have evolved and adapted to grow and better serve our customers in a dynamic and evolving industry. The actions we are announcing today will give the company the financial foundation to continue setting the standard with industry expertise, exceptional service and comprehensive technology solutions for many years to come.

“We are grateful to our employees for their hard work and continued dedication to IPC clients throughout this process. We also thank our customers, suppliers and other business partners for their support as we focus on aligning IPC’s financial structure for long-term success, ”concludes Santella.

IPC’s professional advisors included Kirkland & Ellis and Evercore.

About the IPC
IPC is a technology and services leader that powers global financial markets. With a customer-centric mindset, IPC brings together one of the largest and most diverse global financial ecosystems spanning all asset classes and market players. As a catalyst for this ecosystem, IPC enables the community to interact, transact and respond to changes and challenges in the marketplace, and we collaborate with our clients to help them make them secure, productive, compliant. and connected. Visit www.ipc.com and follow us on LinkedIn and Twitter (@IPC_Systems_Inc).

About SVPGlobal
SVPGlobal is a global investment firm focused on distressed debt, special situations and private equity opportunities with over $ 17 billion in assets under management. The company, created by Victor Khosla in 2001, had around 130 employees, including around 50 investment professionals, located in its main offices in Greenwich (CT), London and a presence in Tokyo. It was one of the first struggling American companies to establish a European office, opening in London in 2004. In total, SVPGlobal invested more than $ 36 billion of capital since its creation in 2001, of which $ 16 billion in Europe, and has conducted over 150 significant transactions. SVPGlobal is a signatory of the Principles for Responsible Investment (PRI) supported by the United Nations. The PRI are recognized as the leading global network of investors committed to integrating environmental, social and governance (ESG) considerations into their investment decisions. Learn more about www.svpglobal.com.

About Centerbridge
Centerbridge is a private investment management firm that uses a flexible approach across all investment disciplines – private equity, private credit and real estate – with the aim of developing the most attractive opportunities for our investors. The firm was founded in 2005 and from July 1, 2021 around $ 31 billion in capital under management with offices in new York and London. Centerbridge is committed to partnering with world-class management teams in targeted industry sectors and geographies. For more information, please visit www.centerbridge.com.

Media contacts:
Ganesh Iyer, Marketing and Strategy Director
[email protected]

Juliana Correa, Marketing director
[email protected]

Certain statements contained in this press release may be forward-looking statements. All forward-looking statements are based on current expectations, assumptions, estimates and projections and involve known and unknown risks and uncertainties. Actual results may differ materially from any future results expressed or implied by these forward-looking statements.

SOURCE IPC Systems, Inc.

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Advisor Best Interests Standard # 68: PTE 2020-02 Compliance: Factors to Consider for a Recommendation for Renewal (Part 4) | Faegre Drinker Biddle & Reath LLP https://hledam.biz/advisor-best-interests-standard-68-pte-2020-02-compliance-factors-to-consider-for-a-recommendation-for-renewal-part-4-faegre-drinker-biddle-reath-llp/ https://hledam.biz/advisor-best-interests-standard-68-pte-2020-02-compliance-factors-to-consider-for-a-recommendation-for-renewal-part-4-faegre-drinker-biddle-reath-llp/#respond Fri, 01 Oct 2021 03:21:42 +0000 https://hledam.biz/advisor-best-interests-standard-68-pte-2020-02-compliance-factors-to-consider-for-a-recommendation-for-renewal-part-4-faegre-drinker-biddle-reath-llp/ This series focuses on the new DOL fiduciary “rule”, which came into effect on February 16. This article, and the following ones, examine the Frequently Asked Questions (FAQ) issued by the DOL to explain the fiduciary definition and conflict of interest exemption. Key points to remember The DOL FAQs generally explain PTE 2020-02 and the […]]]>

This series focuses on the new DOL fiduciary “rule”, which came into effect on February 16. This article, and the following ones, examine the Frequently Asked Questions (FAQ) issued by the DOL to explain the fiduciary definition and conflict of interest exemption.

Key points to remember

  • The DOL FAQs generally explain PTE 2020-02 and the expanded definition of fiduciary boards.
  • FAQ 15 explains DOL’s opinion on the factors to consider in determining whether a roll recommendation is in the best interests of a plan member. One of the requirements is that the investment professional and the financial institution obtain information about the plan and the member’s account. The preferred approach is to use “primary” data (i.e. actual and current diet data), but in some circumstances “alternative” or secondary data may be used.
  • The requirement that a recommendation to renew a plan to an IRA meet the best interest standard of care already applies, since the DOL’s no-application policy delays the conditions for exemption but not the termination. fiduciary definition.

Background

DOL forbidden transaction exemption, (PTE) 2020-02 (Improving investment advice for workers and retirees), allows investment advisers, brokers, banks and insurance companies (“financial institutions”) and their representatives (“investment professionals”) to receive conflicting compensation resulting from non-trust investment advice. discretionary pension plans, members and IRA owners (“retirement investors”). In addition, in the preamble to the PTE, the DOL announced an expanded definition of fiduciary boards, which means that many other financial institutions and investment professionals will be fiduciaries of their recommendations to retirement investors and therefore will need the protection provided by the exemption.

In April, the DOL published FAQs that explain the fiduciary interpretation and the conditions of the exemption.

This article discusses FAQ 15, a question and answer from DOL on the factors that must be considered in meeting the best interest standard of care for reappointment recommendations. The first article in this sub-series, Best Interest # 65, cited all questions and answers. This week’s article focuses on using primary plan data and alternative plan data.

When most people think of the plan data a trustee needs to recommend a rollover, their thoughts automatically turn to disclosure form 404a-5. However, that is not what the guide says. Here is a quote from FAQ 15:

To meet the documentation requirement for transfers from a benefit plan to an IRA, investment professionals and financial institutions should make diligent and prudent efforts to obtain information about the benefit plan. existing social policies and the interests of the participant therein.

As you can see from this quote, the requirement is that the participant’s plan and account information be reviewed. And earlier in FAQ 15, the DOL explains that the information required on the plan is: the fees and expenses associated with both the plan, whether the employer pays some or all of the administrative costs of the plan, the different levels of service and the investments available under the plan.

It’s pretty clear… information is needed on the plan’s current investments, services, and spending (which I call “master” data). Further details on the requirement are explained in the FAQ, where the DOL says: When considering alternatives to a rollover, the financial institution and investment professional should generally not focus solely on the retirement investor’s existing investment allocation, without any consideration of other options. investment in the plan.

Thus, the position of the DOL is that in order to have a compliant and prudent process for recommending a transfer from a plan to an IRA, one of the requirements is that the investment professional and the financial institution obtain information on :

  • Investments in the plan;
  • The allocation of the member’s assets;
  • Plan fees and expenses; and
  • The services in the plan.

But how can the investment professional get this “key” information?

Concretely, there are several ways:

  • From a 404a-5 disclosure statement;
  • At the benefit office of the participant’s employer (with the assistance of the participant);
  • From the plan’s website (with the help of the member); Where
  • From a sales department which probably obtains the information from the regime’s archivist.

In the above quote, the DOL stated that financial institutions and investment professionals should make a diligent and careful effort to obtain primary information. Is it “diligent and prudent” to just ask? Should the member be advised that they can obtain copies from their plan’s website or from their employer’s benefits office? These questions were not answered by the DOL… but they may be at some point.

In FAQ 15, the DOL uses an example of obtaining information from disclosure 404a-5: In general, this information should be readily available due to departmental regulations requiring disclosure of plan information to plan members (see 29 CFR 2550.404a-5).

However, this is only one way to do it.

But what if none of these options work?

Then, with appropriate warnings to the participant, “alternative” data can be used. FAQ 15 says: If the retirement investor does not provide the information, even after a full explanation of its meaning, and the information is not readily available, the financial institution and the investment professional should a reasonable estimate expenses, asset values, risks and returns based on publicly available information. The financial institution and the investment professional must document and explain the assumptions used and their limitations.

As explained in bold text, in order to use alternative data, the financial institution and the investment professional:

  • Must provide the member with a “full explanation of the importance” of not providing current plan information, and
  • Must document and explain the assumptions used and their limitations.

Even then, there are unanswered questions. For example, this process allows alternative data to be used for “a reasonable estimate of expenses, asset values, risks and returns”. (This data could come from a benchmarking service or from a Form 5500 previously filed by the plan.) But what does that really mean? Does the use of alternative data mean that it is no longer necessary to have information on how the participant is invested in their account? What about the range of investments in the plan? What about the plan’s services? Unfortunately, the DOL did not answer these questions, leaving financial institutions at risk – at least, the risk of the unknown – if they do not have this information. At the very least, it underscores the importance of obtaining primary data, whether it comes from a participant’s quarterly statement, 404a-5 disclosure statement, a sales department, or otherwise.

Final thoughts

The bottom line is that the “master” data clearly meets the DOL’s plan information requirements for a renewal recommendation. However, it is not clear whether the alternative meets all the requirements for obtaining participant plan and account information, or only the requirement, for example, for information on expenses. It is also unclear how much effort is required to meet the “diligent and prudent effort” requirement.

Accordingly, the effort to obtain primary data must be demonstrably diligent and careful (and possibly documented), and warnings to the participant must be complete and meaningful.

A reasonable reading of the guidelines is that the DOL understands that in some cases alternate data may be used. It therefore wants to be a way. But, to take this route, the additional requirements of the DOL must be met.


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